There are many factors to consider about crushing Hazardous Medications which should be determined by pharmacists at each hospital. Guidelines about compounding various levels of hazardous drugs are contained in USP Chapters <800> and <795>. Many drugs can safely be crushed on the hospital floor with the RxCrush device, rather than in controlled atmosphere pharmacy conditions. For Hazardous Medications, RxCrush is recommended to add additional control to the manipulation process.
Our RxCrush customers follow policies which often depends on the equipment and layout of pharmacists in their own hospitals and guided by USP<800> and other chapters.
Generally, drugs without a NIOSH Hazardous Drug classification can be compounded with RxCrush on the hospital floor. RxCrush contains the crushing process better than any other device because the RxCrush Pill Pouch contains the solid medications and fluids throughout the manipulation process. preparation.
NIOSH Table 1, 2, 3 and 4 drugs from tables require more care. There is a list compiled by NIOSH for the various levels of hazardous drugs. The list can be found here: https://www.cdc.gov/niosh/docs/2010-167/pdfs/2010-167.pdf. It is the drugs on this list that should be approved by pharmacists.
USP<800> and <795> mandates as much Personal Protection should be used when crushing medications as possible given the resources of the hospital.
RxCrush makes the containers and the crusher for pill crushing but don't have the scope to set crushing protocol.