Users are successfully crushing 5 to 8 pills at a time in the pouches. More pills will require more flushing cycles. Flushing the contents of the pouch is achieved by filling the syringe with liquid, injecting into the pouch, shaking and removing contents multiple times until all dissolved medication is captured.
As of 2/28/2022 every pharmacist surveyed from among RxCrush customers, recommends that only one medication be crushed in a dose. That may include several pills of the same medication but not a mix of different medications.
Rx Crush Pharmacist users have different opinions about how many pills can be crushed in one dose. Several are recommending crushing only one pill at time, depending on the medications. Others are allowing as many pills as can be effectively crushed and dissolved at one time.